Schizophrenia: Manifestations, incidence and course in different cultures: A World Health Organization ten-country study.

Abstract: Studied schizophrenia (SCZ) and related disorders in 10 countries (Colombia, Czechoslovakia, Denmark, India, Ireland, Japan, Nigeria, the USSR, the UK, and the US), based on an initial and 1- and 2-yr follow-up examinations of 1,379 patients (aged 15–54 yrs). Early behavioral manifestations of psychotic illness were similar across the geographical centers. 82% of the cases were assigned to CATEGO classes S, P, or O; 56% had CATEGO class S+ ("nuclear SCZ"). Present State Examination profiles were similar in the developed and developing countries. In all study areas, the age- and sex-specific curves of the incidence of SCZ followed a similar pattern. On 5 of 6 outcome dimensions, Ss in developing countries had a better prognosis than Ss in developed countries. Type of onset and setting (developing or developed country) were the most important predictors of 2-yr course and outcome. (PsycINFO Database Record (c) 2012 APA, all rights reserved)

Click to view the articleView Article
Home of the Culturally Adapted Psychoeducation project for families of patients with first-episode psychosis and The Culture and Psychosis Working Group